Features front page news sports business lifestyles opinion a&e all sections front page news sports business lifestyles opinion a&e home > featured articles > disease new lead on huntington's disease january 10, 2010 | by shari roan, tribune newspapers there's no cure or treatment for huntington's disease, one of the most devastating genetic disorders. viagra without a doctor prescription But a study in animals suggests a possible new approach to someday treating the disorder. viagra tadalafil drug Researchers at the university of california at los angeles have identified a molecular switch that prevents the disease from developing in mice. viagra online without prescription The study was published in late december in the journal neuron. viagra tadalafil drug Huntington's disease causes progressive neurological damage. viagra tadalafil drug Symptoms first appear in midlife and gradually rob patients of their ability to talk, walk, think and even swallow. The disease is caused by an inherited mutation in the polyglutamine region of a protein called huntingtin. In a first phase of research, scientists at the university of california at irvine showed that two amino acids near the beginning of the huntingtin protein can be altered by a chemical process called phosphorylation. order viagra The ucla researchers then tested whether phosphorylation could influence the disease process. viagra 20 dosage Using two mice with the huntington's disease mutation, they modified the two amino acids in different ways -- one to mimic phosphorylation and one to prevent it. viagra canada They found that preventing phosphorylation caused the mice to develop symptoms of the disease, but mimicking it did not. Similar research, performed at the university of pittsburgh, has also shown that mimicking phosphorylation of a fragment of the huntingtin gene reduces the protein's tendency to form clumps. viagra cost insurance "we were surprised to find that subtle modification of only two amino acids in this very large protein can prevent the onset of disease," lead author of the study x. William yang said in a news release. buy viagra cheap Featured articles decoding the diabetic diet for heart health, fish oil pills not the answer: study fda tests find arsenic in rice more: cooking tips to possibly lessen risk of. viagra canada online